Changes in expression of adenyl cyclase activity in human endometrium during hormone replacement therapy and ovarian stimulation
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چکیده
منابع مشابه
Changes in expression of adenyl cyclase activity in human endometrium during hormone replacement therapy and ovarian stimulation.
We have investigated membrane fractions prepared from human endometrium for activity of the signalling adenyl cyclase (AC). We characterized the AC guanine nucleotide-binding proteins (G proteins) and examined the changes in AC activity during evaluation cycles of oestrogen and progesterone replacement therapy as well during ovarian stimulation cycles. AC activity was determined by the conversi...
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The inflammatory mediators PGE2, DC-PGI2 and histamine as well as the beta-adrenergic drugs isoprenaline and salbutamol increase intracellular cyclic AMP-concentrations whereas Platelet Activating Factor does not induce any change in adenyl cyclase activity of normal human alveolar macrophages. Functional H2-histaminergic and beta 2-adrenergic receptor-subtypes are coupled to macrophage adenyl ...
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Modern hormone replacement therapy (HRT) regimens contain oestrogen and progestogen, given either in a cyclical or continuous combined manner. Most endometrial biopsies from women on sequential HRT show weak secretory features. Approximately 15% show proliferative activity, although this figure may be less if more than nine days of progestogen is given in each cycle. A small proportion will sho...
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ژورنال
عنوان ژورنال: Molecular Human Reproduction
سال: 1999
ISSN: 1460-2407
DOI: 10.1093/molehr/5.10.955